Food Challenges

DBPCFC is the gold standard for diagnosing AFR and is usually performed by an allergist/immunologist familiar with the management of anaphylaxis. A positive chal­lenge does not necessarily identify the mechanism of the reaction (IgE-, non-IgE-, or non-immune-mediated reaction). Food challenges are contraindicated In sus­pected food-Induced anaphylaxis. Good history and consistent SPT are usually suffi­cient to establish a diagnosis without a food challenge. With vague history and inconclusive SPT, an open challenge may be indicated, followed, if positive, by a blinded challenge. Details of food-challenge techniques are available in standard allergy textbooks

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